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Prevalence and burden of hepatitis B co-infection among people living with HIV: a global systematic review and meta-analysis

Lead researchers

Anatomical diagram showing hepatitis b virus attacking the liver


About the project

Globally there are 35 million people living with HIV and 248 million people with chronic hepatitis B (HBV) infection (HbsAg positive). However, little is known about the extent of HIV-HBsAg infection. There is a need to establish the global burden of HBsAg co-infection among people living with HIV to:

  • characterise the populations at risk 
  • identify the geographical regions most affected 
  • inform national and regional screening programmes as well as clinical management.

Project aim

To describe the epidemiology and global burden of HBsAg co-infection in people living with HIV by conducting a global systematic review and meta-analysis.

Anticipated impacts

Data on the global burden of HBV co-infection among people living with HIV will inform national and regional screening programmes and clinical management.

Funders

Research team

  • Philippa Easterbrook, Professor (World Health Organization)
  • Clare French, Dr (University of Bristol)
  • Bethan McDonald, Dr (Oxford University Hospitals NHS Foundation Trust and London School of Hygiene & Tropical Medicine)
  • Catherine McGowan, Dr (Save the Children UK) 
  • Jason Ong, Professor (Monash University and London School of Hygiene & Tropical Medicine)
  • Lucy Platt, Dr (London School of Hygiene & Tropical Medicine)
  • Keith Sabin, Dr (UNAIDS) 
  • Jack Stone, Mr (University of Bristol)
  • Adam Trickey, Mr (University of Bristol)
  • Peter Vickerman, Professor (University of Bristol)